Six Senses Douro Valley, Portugal
While not as remote as the other properties, Six Senses’ Duoro Valley has the bonus of being right in the heart of Portugal’s wine-producing regions. You’re still surrounded by nature though, the property overlooks a river and verdant vineyards that offer activities like winery visits and the traditional grape-stomping, which marks the start of a vintage. If wine isn’t enough of an elixir, the property’s 10 treatment rooms offer locally-inspired therapies like grape and citrus fruit-based ones. Couple that with a heated indoor pool, outdoor pool, and a well-equipped gym and you’ll be burning off enough calories to indulge a little at one of the hotel’s locavore, provenance-led restaurants.